One week before GAZYVA infusion:

  • Tell your doctor about all the medicines you take, including prescription and non-prescription medicine, vitamins, and herbal supplements
  • Speak to your doctor if you take medications to control your blood pressure. Your doctor may ask you to not take them on the day of your GAZYVA® (obinutuzumab) infusion
  • Arrange a ride—after your infusion, you may feel drowsy or dizzy. It is a good idea to have someone else drive you home

One day before GAZYVA infusion:

  • Remember to follow any changes your doctor made to your regular medication schedule

The day of your GAZYVA infusion

At home:
  • Wear or bring loose clothing so you can be comfortable during your infusion
  • Pack food and drink—bringing some snacks or a packed meal can help you get through the day
  • Bring a book or activities to help pass the time
At the clinic or infusion center:
  • Take the medications prescribed by your doctor to help reduce the side effects of the infusion process
  • Relax during your infusion, but be aware of what is happening to your body. Tell your doctor or nurse right away if you feel any side effects, including the symptoms of an infusion reaction

Infusion-Related Reactions (IRRs)

These side effects may occur during or within 24 hours of any GAZYVA infusion. Some IRRs can be serious. These may include, but are not limited to, severe allergic reactions (anaphylaxis), acute life-threatening breathing problems, or other life-threatening IRRs.

If you have a reaction, your infusion will either be slowed or stopped until your symptoms are resolved. Most patients are able to complete infusions and receive medication again. However, if the IRR is serious, the infusion of GAZYVA will be permanently stopped.

Your healthcare team will take steps to help lessen any side effects you may have to the infusion process. You may be given medicines to take before each GAZYVA treatment.

Symptoms of IRRs may include:
  • Fast heartbeat
  • Tiredness
  • Dizziness
  • Headache
  • Redness of the face
  • Nausea
  • Chills
  • Fever
  • Vomiting
  • Diarrhea
  • Rash
  • High blood pressure
  • Low blood pressure
  • Difficulty breathing
  • Chest discomfort