Non-Hodgkin’s lymphoma (NHL) is a blood cancer that involves lymphocytes—white blood cells that help fight infections. Abnormal lymphocytes build up in the lymph nodes, bone marrow, and spleen. NHL can be indolent (slow-growing) or aggressive.

Follicular lymphoma is the most common type of indolent NHL and can be a chronic disease.

Understanding relapsed or refractory follicular lymphoma

If your doctor refers to your follicular lymphoma as “relapsed,” this might mean it has returned after responding to previous treatment. If your follicular lymphoma has not responded to previous treatment, your doctor may refer to your disease as “refractory.”